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Targeted Therapy Medications

Targeted therapy, a type of precision medicine, works against cancer with specific gene mutations or other unique characteristics. Researchers have identified hundreds of driver mutations that contribute cancer progression and are developing medications to block their activity. Usually this type of treatment interferes with processes required for cancer cells to grow and spread.

*generic or biosimilar available

E experimental


DRUG Adcetris
Adcetris (brentuximab vedotin)
GENERIC NAME brentuximab vedotin
COMPANY Seattle Genetics
DRUG Afinitor*
Afinitor, everolimus
GENERIC NAME everolimus
COMPANY Novartis
DRUG Alecensa
Alecensa (alectinib)
GENERIC NAME alectinib
COMPANY Genentech
DRUG Aliqopa
Aliqopa copanlisib
GENERIC NAME copanlisib
COMPANY Bayer
DRUG Alunbrig
Alunbrig, brigatinib
GENERIC NAME brigatinib
COMPANY Takeda
DRUG Arzerra
Arzerra ofatumumab
GENERIC NAME ofatumumab
COMPANY Novartis
DRUG Avastin*
Avastin, bevacizumab
GENERIC NAME bevacizumab
COMPANY Genentech
DRUG Ayvakit
GENERIC NAME avapritinib
COMPANY Blueprint Medicines
DRUG Balversa
Balversa, erdafitinib, FGFR
GENERIC NAME erdafitinib
COMPANY Janssen
DRUG Besponsa
Besponsa, inotuzuma ozogamicin
GENERIC NAME inotuzuma ozogamicin
COMPANY Wyeth-Pfizer
DRUG Blenrep
GENERIC NAME belantamab mafodotin
COMPANY GlaxoSmithKline
DRUG Blincyto
Blincyto, blinatumomab, Amgen, leukemia
GENERIC NAME blinatumomab
COMPANY Amgen
DRUG Bosulif
Bosulif, bosutinib
GENERIC NAME bosutinib
COMPANY Pfizer
DRUG Braftovi
Braftovi, encorafenib
GENERIC NAME encorafenib
COMPANY Array BioPharma/Pfizer
DRUG Brukinsa
Brukinsa, zanubrutinib
GENERIC NAME zanubrutinib
COMPANY BeiGene
DRUG Cabometyx
Cabometyx, cabozantinib
GENERIC NAME cabozantinib
COMPANY Exelixis
DRUG Calquence
Calquence (acalabrutinib)
GENERIC NAME acalabrutinib
COMPANY AstraZeneca
DRUG Campath*
Campath, alemtuzumab
GENERIC NAME alemtuzumab
COMPANY Berlex
DRUG Copiktra
GENERIC NAME duvelisib
COMPANY Verastem
DRUG Cotellic
Cotellic, cobimetinib
GENERIC NAME cobimetinib
COMPANY Genentech
DRUG Cyramza
Cyramza, ramucirumab
GENERIC NAME ramucirumab
COMPANY Eli Lilly
DRUG Danyelza
Danyelza, naxitamab
GENERIC NAME naxitamab
COMPANY Y-mAbs Therapeutics
DRUG Darzalex, Darzalex Faspro
Darzalex, daratumumab, multiple myeloma
GENERIC NAME daratumumab
COMPANY Janssen Therapeutics
DRUG Daurismo
Daurismo, glasdegib
GENERIC NAME glasdegib
COMPANY Pfizer
DRUG Elzonris
GENERIC NAME tagraxofusp-erzs
COMPANY Stemline Therapeutics
DRUG Empliciti
Empliciti elotuzumab
GENERIC NAME elotuzumab
COMPANY Bristol-Myers Squibb
DRUG Enhertu
GENERIC NAME fam-trastuzumab deruxtecan-nxki
COMPANY Daiichi Sankyo/AstraZeneca
DRUG Erbitux
GENERIC NAME cetuximab
COMPANY Eli Lilly
DRUG Fotivda
Fotivda, tivozanib
GENERIC NAME tivozanib
COMPANY Aveo Oncology
DRUG Gavreto
Gavreto, pralsetinib
GENERIC NAME pralsetinib
COMPANY Blueprint/Genentech
DRUG Gazyva
GENERIC NAME obinutuzumab
COMPANY Genentech
DRUG Gilotrif
Gilotrif, afatinib
GENERIC NAME afatinib
COMPANY Boehringer Ingelheim
DRUG Gleevec*
Gleevec, imatinib
GENERIC NAME imatinib
COMPANY Novartis
DRUG Herceptin*
Herceptin, trastuzumab
GENERIC NAME trastuzumab
COMPANY Genentech
DRUG Ibrance
Ibrance, palbociclib
GENERIC NAME palbociclib
COMPANY Pfizer
DRUG Iclusig
Iclusig, ponatinib
GENERIC NAME ponatinib
COMPANY Pfizer
DRUG Idhifa
Idhifa, enasidenib
GENERIC NAME enasidenib
COMPANY Celgene-Agios
DRUG Imbruvica
Imbruvica ibrutinib
GENERIC NAME ibrutinib
COMPANY Janssen
DRUG Inlyta
Inlyta, axitinib
GENERIC NAME axitinib
COMPANY Pfizer
DRUG Iressa
Iressa, gefitinib
GENERIC NAME gefitinib
COMPANY AstraZeneca
DRUG Kadcyla
Kadcyla, ado-trastuzumab emtansine
GENERIC NAME ado-trastuzumab emtansine
COMPANY Genentech
DRUG Kisqali
GENERIC NAME ribociclib
COMPANY Novartis
DRUG Koselugo
Koselugo, selumetinib
GENERIC NAME selumetinib
COMPANY AstraZeneca
DRUG Kyprolis
Kyprolis carfilzomib
GENERIC NAME carfilzomib
COMPANY Amgen
DRUG Lenvima
Lenvima, lenvatinib
GENERIC NAME lenvatinib
COMPANY Eisai
DRUG Lorbrena
Lorbrena, lorlatinib
GENERIC NAME lorlatinib
COMPANY Pfizer
DRUG Lumoxiti
Lumoxiti moxetumomab pasudotox
GENERIC NAME moxetumomab pasudotox
COMPANY AstraZeneca
DRUG Lynparza
Lynparza, olaparib
GENERIC NAME olaparib
COMPANY AstraZeneca
DRUG Margenza
Margenza margetuximab MacroGenics
GENERIC NAME margetuximab
COMPANY MacroGenics
DRUG Mekinist
Mekinist, trametinib
GENERIC NAME trametinib
COMPANY Novartis
DRUG Mektovi
Mektovi, binimetinib
GENERIC NAME binimetinib
COMPANY Pfizer
DRUG Monjuvi
Monjuvi, tafasitamab, MorphoSys
GENERIC NAME tafasitamab
COMPANY Morphosis/Incyte
DRUG Mylotarg
Mylotarg, gemtuzumab ozogamicin
GENERIC NAME gemtuzumab ozogamicin
COMPANY Pfizer/Wyeth
DRUG Nerlynx
Nerlynx, neratinib
GENERIC NAME neratinib
COMPANY Puma
DRUG Nexavar
Nexavar, sorafenib
GENERIC NAME sorafenib
COMPANY Bayer
DRUG Ninlaro
Ninlaro ixazomib
GENERIC NAME ixazomib
COMPANY Takeda
DRUG Padcev
Padcev, enfortumab vedotin
GENERIC NAME enfortumab vedotin-ejfv
COMPANY Astellas/Seattle Genetics
DRUG Pemazyre
Pemazyre, pemigatinib
GENERIC NAME pemigatinib
COMPANY Incyte
DRUG Perjeta
Perjeta, pertuzumab
GENERIC NAME pertuzumab
COMPANY Genentech
DRUG Phesgo
Doctor fills injection syringe with vaccine
GENERIC NAME Pertuzumab/trastuzumab/hyaluronidase
COMPANY Genentech
DRUG Piqray
Piqray, alpelisib
GENERIC NAME alpelisib
COMPANY Novartis
DRUG Polivy
Polivy, polatuzumab vedotin
GENERIC NAME polatuzumab vedotin-piiq
COMPANY Genentech
DRUG Portrazza
Portrazza, necitumumab
GENERIC NAME necitumumab
COMPANY Eli Lilly
DRUG Qinlock
Qinlock, ripretinib
GENERIC NAME ripretinib
COMPANY Deciphera
DRUG Retevmo
Retevmo, selpercatinib
GENERIC NAME selpercatinib
COMPANY Eli Lilly and Company
DRUG Rituxan*
Rituxan rituxumab
GENERIC NAME rituxumab
COMPANY Genentech
DRUG Rozlytrek
Rozlytrek, ectrectinib
GENERIC NAME entrectinib
COMPANY Roche/Genentech
DRUG Rubraca
Rubraca
GENERIC NAME rucaparib
COMPANY Clovis Oncology
DRUG Rydapt
Rydapt, midostaurin
GENERIC NAME midostaurin
COMPANY Novartis
DRUG Sarclisa
Sarclisa, isatuximab
GENERIC NAME isatuximab-irfc
COMPANY Sanofi-Aventis
DRUG Sprycel
Sprycel, dasatinib
GENERIC NAME dasatinib
COMPANY Bristol-Myers Squibb
DRUG Stivarga
Stivarga, regorafenib
GENERIC NAME regorafenib
COMPANY Bayer
DRUG Sutent
Sutent, sunitinib
GENERIC NAME sunitib
COMPANY Pfizer
DRUG Tabrecta
Tabrecta, capmatinib
GENERIC NAME capmatinib
COMPANY Novartis
DRUG Tafinlar
Tafinlar, dabrafenib
GENERIC NAME dabrafenib
COMPANY Novartis
DRUG Tagrisso
Tagrisso, osimertinib
GENERIC NAME osimertinib
COMPANY AstraZeneca
DRUG Talzenna
Talzenna, talazoparib
GENERIC NAME talazoparib
COMPANY Pfizer
DRUG Tarceva
Tarceva, erlotinib
GENERIC NAME erlotinib
COMPANY Genentech/Astellas
DRUG Tasigna
Tasigna, nilotinib
GENERIC NAME nilotinib
COMPANY Novartis
DRUG Tazverik
Tazeverik, tazemetostat, epithelioid sarcoma, sarcoma
GENERIC NAME tazemetostat
COMPANY Epizyme
DRUG Tibsovo
Tibsovo, ivosidenib, Agios
GENERIC NAME ivosidenib
COMPANY Agios
DRUG Torisel
GENERIC NAME temsirolimus
COMPANY Pfizer/Wyeth
DRUG Trodelvy
Trodelvy, sacituzumab govitecan
GENERIC NAME sacituzumab govitecan
COMPANY Immunomedics
DRUG Tukysa
Tukysa, tucatinib
GENERIC NAME tucatinib
COMPANY Seattle Genetics
DRUG Turalio
Turalio pexidartinib
GENERIC NAME pexidartinib
COMPANY Daiichi Sankyo
DRUG Tykerb
Zejula, niraparib
GENERIC NAME lapatanib
COMPANY Novartis
DRUG Vectibix
Vectibix, panitumumab
GENERIC NAME panitumumab
COMPANY Amgen
DRUG Velcade
Velcade bortezomib
GENERIC NAME bortezomib
COMPANY Takeda
DRUG Venclexta
Venclexta, venetoclax
GENERIC NAME venetoclax
COMPANY AbbVie-Genentech
DRUG Verzenio
Verzenio, abemaciclib
GENERIC NAME abemaciclib
COMPANY Eli Lilly
DRUG Vitrakvi
Vitraki, larotrectinib
GENERIC NAME larotrectinib
COMPANY Bayer
DRUG Vizimpro
Vizimpro dacomitinib
GENERIC NAME dacomitinib
COMPANY Pfizer
DRUG Votrient
Votrient, pazopanib
GENERIC NAME pazopanib
COMPANY Novartis
DRUG Xalkori
Xalkori, crizotinib
GENERIC NAME crizotinib
COMPANY Pfizer
DRUG Xospata
GENERIC NAME gilteritinib
COMPANY Astellas
DRUG Zaltrap
Zaltrap, ziv-aflibercept
GENERIC NAME ziv-aflibercept
COMPANY Sanofi/Genzyme
DRUG Zejula
Zejula, niraparib
GENERIC NAME niraparib
COMPANY Tesaro
DRUG Zelboraf
Zelboraf (vemurafenib)
GENERIC NAME vemurafenib
COMPANY Genentech
DRUG Zydelig
Zydelig idelalisib
GENERIC NAME idelalisib
COMPANY Gilead Sciences
DRUG Zykadia
Zykadia, ceritinib
GENERIC NAME ceritinib
COMPANY Novartis

Last Reviewed: July 3, 2019


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