Generic Name: bicalutamide
Drug Class: Hormone Therapy Medications
Company: AstraZeneca
Approval Status: Approved
Generic Version Available: Yes
Drug Indication
Casodex is an androgen receptor inhibitor approved for metastatic prostate cancer.
General Info
Testosterone and other male hormones (androgens) stimulate prostate cancer growth. Medical or surgical castration reduces testosterone levels, but other cells in the body can still make androgens. Medications like Casodex bind to androgen receptors in prostate cells and prevent them from sending chemical signals that trigger cancer cell proliferation. They are usually combined with GnRH agonists to stop testosterone production, known as androgen deprivation therapy (ADT).
Dosage
Dosing Info: Casodex is taken as a once-daily pill.
Side Effects
Common side effects include hot flashes, pain, weakness, constipation, diarrhea, nausea, swelling and nighttime urination. Casodex may cause breast pain and enlargement (gynecomastia). Potential serious side effects include liver toxicity and a higher risk of diabetes.
For More Info: https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/076932s000lbl.pdf
Co-Pay Program Info: https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/076932s000lbl.pdf
Patient Assistance Program Info: https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/076932s000lbl.pdf
Last Reviewed: September 19, 2018
